Sperm cell granuloma, also termed epididymitis nodosa, is a benign lesion that can occur in the scrotum. They can particularly occur in those with a prior vasectomy (occurs after vasectomy in up to 40% of patients 2).
It is considered a form of chronic epididymitis which occurs secondary to inflammation, trauma, and/or a vasectomy. A granulomatous reaction forms secondary to extravasated sperm cells
- 1. Frates MC, Benson CB, DiSalvo DN et-al. Solid extratesticular masses evaluated with sonography: pathologic correlation. Radiology. 1997;204 (1): 43-6. doi:10.1148/radiology.204.1.9205221 - Pubmed citation
- 2. Dogra VS, Gottlieb RH, Oka M et-al. Sonography of the scrotum. Radiology. 2003;227 (1): 18-36. Radiology (full text) - doi:10.1148/radiol.2271001744 - Pubmed citation