Radiation-induced breast changes

Last revised by Dr Bruno Di Muzio on 16 Apr 2019

Radiation-induced breast changes are a consequence of radiotherapy toxicity over the breast tissues either related to targeted breast cancer treatment or other thoracic malignancies (eg. lung cancer). 

The radiation-induced breast changes may be seen in either dedicated breast imaging or CT chest performed for follow-up of other thoracic malignancies. 

Radiation-induced breast malignancy is rare 1-3 and possible induced tumors include:

Differential diagnosis is mainly considered in those patients treating breast cancer, as it may be difficult to distinguish the above-mentioned breast changes from: 

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Cases and figures

  • Case 1: gross dystrophic calcification
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