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Revision 11 for 'Perineural spread of tumor'

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Perineural tumor spread

Perineural tumor spread is a form of metastatic disease in which primary tumors cells spread along the tissues of the nerve sheath, being a well recognized phenomenon in head and neck cancers. 


Perineural tumor spread is more frequently associated with 1,2,5:

Radiographic features


Perineural tumor spread could be characterized as nerve thickening, widening of the neural foramen, loss of the fat surrounding the nerve and enhancement of the nerve after contrast administration. 

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