Medial lemniscus

The medial lemniscus, also known as Reil's band, is an ascending bundle of myelinated axons from the gracile and cuneate nuclei after they decussate in the medulla oblongata

Gross anatomy

It is part of the larger dorsal column-medial lemniscus pathway, important for conveying the sensation for fine (discriminative) touch, vibration and conscious proprioception. 


Gracile and cuneate nuclei are second-order sensory neurons which receive peripheral input from the first-order neurons in the gracile fasciculus and the cuneate fasciculus of the dorsal columns. These nuclei send out axons called the internal arcuate fibers, which become the medial lemniscus after they decussate in the medulla oblongata 1,2.

Medial lemniscus terminates in the ventral posterior nucleus of the thalamus, where it synapses with the third-order neurons which transmit information to the postcentral gyrus of the cerebral cortex 1,2.​

Anatomy: Brain

Anatomy: Brain

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Article information

rID: 56479
Section: Anatomy
Tag: refs
Synonyms or Alternate Spellings:
  • Reil's band
  • Reil's ribbon

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