Gasperini syndrome

Gasperini syndrome is a rare pontine stroke syndrome that involves the caudal pons tegmentum.

Classically, the syndrome presents with 1-3:

  • involvement of the CN V nucleus: ipsilateral facial sensory loss
  • involvement of the CN VI nucleus: ipsilateral impaired eye abduction
  • involvement of the CN VII nucleus: ipsilateral facial palsy and hyperacusis
  • involvement of the CN VIII nucleus: vertigo and ipsilateral nystagmus
  • involvement of the spinothalamic tract: contralateral hemi-sensory impairment

A lesion of the caudal pons tegmentum is usually caused by an ischemic stroke, usually due to occlusion of either pontine branches of the basilar artery or the long circumferential branch of the anterior inferior cerebellar artery 1,2, but can also be seen due to demyelination or hemorrhage 3

Lesions are in the caudal pons tegmentum with imaging characteristics depending on underlying cause 2,3.

The syndrome was first described by Ubaldo Gasperini (1880-1918), an Italian physician, in 1912 1,4.

Stroke and intracranial haemorrhage
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Article information

rID: 58856
Section: Syndromes
Synonyms or Alternate Spellings:
  • Gasperini's syndrome

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