Fibrosarcoma of the breast
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Fibrosarcoma of the breast is a type of malignant stromal sarcoma that rarely occurs as a primary tumor within the breast.
A fibrosarcoma is composed of immature mesenchymal elements surrounded by a collagenous substance. It is a type of breast sarcoma with a predominant “herringbone” growth pattern created by elongated spindle cells arranged in broad interdigitating sheets, bands, or fascicles. Some fibrosarcomas lack this classic herringbone pattern and consist instead of a more loosely structured fibroblastic proliferation.
Fibrosarcomas are often seen as a non-spiculated, dense breast mass with largely indistinct borders, although some borders may be sharp. There are no specific mammographic features to distinguish these from round breast carcinomas or non-calcified fibroadenomas 1.
- 1. Elson BC, Ikeda DM, Andersson I et-al. Fibrosarcoma of the breast: mammographic findings in five cases. AJR Am J Roentgenol. 1992;158 (5): 993-5. AJR Am J Roentgenol (abstract) - Pubmed citation
- 2. Lee JY, Kim DB, Kwak BS et-al. Primary fibrosarcoma of the breast: a case report. J Breast Cancer. 2011;14 (2): 156-9. doi:10.4048/jbc.2011.14.2.156 - Free text at pubmed - Pubmed citation
- 3. Payan HM, England DM. Fibrosarcoma mimicking breast fibromatosis. Am J Med Genet Suppl. 1987;3 : 257-62. - Pubmed citation
- 4. Santamaría G, Velasco M, Bargalló X et-al. Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 2010;30 (2): 533-48. doi:10.1148/rg.302095044 - Pubmed citation