Encephalomalacia is term given to describe softening or loss of brain parenchyma with or without surrounding gliosis, as a late manifestation of injury.
- serve as a focus of seizure
Encephalomalacia is the end result of liquefactive necrosis of brain parenchyma following insult, usually occurring after cerebral ischemia, cerebral infection, hemorrhage, traumatic brain injury, surgery or other insults. It is not synonymous with gliosis, which is the proliferation of glial cells in response to injury.
- region of hypoattenuation
- volume loss
- can occur anywhere however has characteristic locations are anteroinferior frontal and temporal lobes
- often associated with gliosis and Wallerian degeneration
Follows CSF signal on all sequences.
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